|Location||Unilateral in 60 to 70 percent; bifrontal or global in 30 percent||Bilateral||Always unilateral, usually begins around the eye or temple|
|Characteristics||Gradual in onset, crescendo pattern; pulsating; moderate or severe intensity; aggravated by routine physical activity||Pressure or tightness which waxes and wanes||Pain begins quickly, reaches a crescendo within minutes; pain is deep, continuous, excruciating, and explosive in quality|
|Patient appearance||Patient prefers to rest in a dark, quiet room||Patient may remain active or may need to rest||Patient remains active|
|Duration||4 to 72 hours||Variable||30 minutes to 3 hours|
|Associated symptoms||Nausea, vomiting, photophobia, phonophobia; may have aura (usually visual, but can involve other senses or cause speech or motor deficits)||None||Ipsilateral lacrimation and redness of the eye; stuffy nose; rhinorrhea; pallor; sweating; Horner’s syndrome; focal neurologic symptoms rare; sensitivity to alcohol|
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